Importance of Vitamin B12, Vitamin D and Iron in CKD and post Kidney Transplant

Posted On Sep 17, 2022 |

Vitamin B12, Vitamin D, and Iron are so important in CKD and post-kidney transplant

Importance of Vitamin B 12, Vitamin D, and Iron in CKD, Kidney Transplant Recipient, and Donor.

A) Vitamin B 12

Vitamin b12 is a water-soluble vitamin involved in metabolism. It cannot be produced by our body but our body needs this vitamin. It is found naturally in animal products, we consume it either orally or through IV sometimes. In the stage of CKD, post kidney transplant or for a kidney donor, it helps in the smooth functioning of nerve cells and is very much needed for RBC formation. When the body is so weak after dialysis or surgery, it gives a raise in the energy level of the body.

It is well known that dialysis and any critical surgery like a kidney transplant affect the heart also, vitamin b12 helps in preventing any heart ailment. It also helps in improving mental performance and getting an efficient memory.

A good level of hemoglobin is necessary for CKD and post-kidney transplant as well as for kidney donors, it helps in the good formation of RBC and prevents Anemia. Deficiency of vitamin b12 can lead to deformation of the cell structure/shape of RBC, which results in obstruction of its movement from bone marrow to the bloodline. The shape of Red blood cells becomes larger and oval in shape instead of small and circular. Transfer of RBC from bone marrow to blood at an inappropriate rate can cause Anemia. Obviously, when a person is facing Anemia in CKD or post kidney transplant, the body is unable to have sufficient RBC to carry oxygen to the important organs of the body like the brain. It has the ability to improve mood and reduce the symptoms of depression. Vitamin b 12 has the ability to tackle bone health issues.

Observations in deficiency of vitamin b12:



Loss of appetite

Muscle weakness

Walking issues

Vision loss

Behavioral problems

Bone health issues

Osteoporosis (especially in females)

B) Vitamin D

It is seen that deficiency of vitamin d takes place in CKD and post-kidney transplant. Kidney donors are supposed to take care of the same. T-cell activation and inflammation in the body may cause rejection of transplanted kidneys, which is caused by a deficiency of vitamin D. So it is important to identify and get treatment for deficiency of vitamin d. It results in worse health outcomes in CKD and post-kidney transplants.

Kidney Transplant and dialysis are the procedures to improve the effects of CKD like bone disorders and mineral disorders.

Vitamin d is responsible for the better regulation of calcium levels in the body after a kidney transplant.

Poor levels of vitamin d in the body can result in an increased risk of metabolic problems including 

High BP, High blood sugar levels, High body fat, and High cholesterol levels. Kidney transplant patients with decreased levels of vitamin d can face endocrine problems like an imbalance in hormones.

Vitamin D can help in better bone health and reduce the risk of graft rejection.

The deficiency of vitamin D can cause the following problems in CKD, post-kidney transplant, and kidney donors:

Cardiovascular diseases

Type 2 diabetes mellitus

Poor graft survival

Bone health issues

C) Iron levels
Iron is responsible for good health and the energy level of the body. The deficiency of iron is causing iron deficiency Anemia. When Red blood cells are in less supply. It results in fatigue issues. It is very common in CKD patients. Sometimes it has been seen in kidney transplant patients and donors. It is dangerous sometimes, if not get treatment on time. It is not easy to detect in the early stage of iron deficiency.

Problems associated with iron deficiency:

Lack of energy
Shortness of breath
Frequent illness
Poor management of body temperature, every time feeling cold
Palpitations (increased pulse rate)
Swallowing issues
Hair loss
Restless leg syndrome ( Uncontrollable urge to move leg)
Deformation in nail shapes
Painful ulcers in the corner of the mouth

    Categories: CKD, dialysis, Kidney, Transplant, Kidney Donor

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